Spurs, who stayed fifth in the table with 36 points from 18 matches, one behind arch-rivals Arsenal and three adrift of third-placed Manchester City, visit 10th-placed Watfor
Lionel Messi, Luis Suarez and Neymar were all on target as holders Barcelona beat Athletic Bilbao 3-1 on Wednesday to overturn a deficit from the first leg and advance to the quarter-finals of the King's Cup.
Manchester United spurned a chance to move into the Premier League's top four after striker Zlatan Ibrahimovic missed a penalty in a 1-1 draw against 10-man Bournemouth on Saturday.
Bournemouth climbed to third place in the Premier League as they won away at Southampton for the first time with a 3-1 triumph in Friday's south-coast derby.
Championship side Derby County hit back from two goals down to beat Premier League Southampton on penalties in an FA Cup third-round replay marred by another VAR controversy on Wednesday.
Sunderland striker Jermain Defoe was recalled to the England squad at the age of 34 on Thursday ahead of next week's friendly in Germany and a World Cup qualifier at home to Lithuania.
Leicester City's Nampalys Mendy fired home the decisive spot kick as they beat Southampton 6-5 on penalties after a 0-0 draw, on Tuesday, to book a League Cup quarter-final with holders Manchester City.
Edge Southampton 2-1 to take campaign to final day of the season.
Manchester City returned to the top of the Premier League on goal difference after coming from behind to draw 1-1 with Southampton at the Etihad Stadium on Sunday.
West Brom, relegated from the Premier League last season, made 11 changes from the side that won at the weekend in the Championship and had five players -- including goalkeeper Alex Palmer -- making their debuts.
Liverpool put their recent troubles behind them, showing touches of their best early-season vibrancy to overcame Arsenal 3-1 at a jubilant Anfield and leapfrog the Gunners into third place in the Premier League on Saturday.
A flash of attacking brilliance from Olivier Giroud and an emphatic header from substitute Alvaro Morata earned Chelsea a 2-0 win over struggling Southampton
Alexis Sanchez and Olivier Giroud were on target as Arsenal won 2-0 at Southampton on Wednesday to move up to fifth in the Premier League and fuel their hopes of a late push for the top four.
Lacazette fired the Gunners ahead in the eighth minute after poor defending by the home side before new signing Gabriel made it 2-0 in the 49th and Aubameyang put the icing on the cake with a superb shot into the top corner.
David Silva scored a late goal as runaway leaders Manchester City won their 13th successive Premier League game and restored their eight-point lead with a 2-1 victory against West Ham United on Sunday.
Wigan, who had beaten three Premier League teams in the Cup including Manchester City in the previous round, could not convert their chances, however.
Southampton's rich vein of form in the Premier League continued as they beat Burnley 3-1 with two goals from Charlie Austin on Sunday while another promoted side, Middlesbrough, fared just as poorly, losing 1-0 at home to Watford.
A late goal by substitute Charlie Austin gave relegation-threatened Southampton a thrilling 3-2 victory over Arsenal on Sunday in new Austrian manager Ralph Hasenhuettl's first home game.
Manchester United's Champions League qualification hopes suffered a blow after an equaliser deep in stoppage time from Michael Obafemi earned Southampton a 2-2 draw in the Premier League at Old Trafford on Monday.
Defeats at Manchester City and Brighton & Hove Albion had left Arsenal down in 11th place but their victory on the south coast lifted them to ninth with 43 points from 31 games -- eight behind fourth-placed Chelsea who were playing City later.
Manchester United's Bruno Fernandes fired home a late penalty to rescue a point for the visitors in a lively 1-1 draw at Tottenham Hotspur in the Premier League on Friday.
Tottenham's task was made all the more difficult two minutes before the interval when forward Son Heung-min was sent off
Leicester City's Premier League title defence got off to a terrible start as they were beaten 2-1 at promoted Hull City, who shrugged off an injury crisis to shock the champions on the opening day of the new season on Saturday
Leicester City recorded the biggest ever English top-flight away win by beating 10-man Southampton 9-0 at a rain-sodden St Mary's to move up to second place in the Premier League on Friday.
Newcastle United's Dutchman Giorginio Wijnaldum scored four times as they won their first Premier League match this season at the ninth attempt by thrashing Norwich City 6-2 to climb off the bottom of the table on Sunday.
Tottenham Hotspur's Harry Kane pounced on a piece of comical defending to secure a 1-0 win over Sunderland in the Premier League on Sunday although he was later wheeled away on a stretcher after suffering an ankle injury.
Chelsea's new signing Gonzalo Higuain netted his first two Premier League goals in Chelsea's 5-0 thrashing of Huddersfield Town while Tottenham Hotspur's Son Heung-min struck late for a 1-0 win over Newcastle United as they moved into second place.
Christian Benteke headed home from close range as Liverpool grabbed a stoppage-time leveller to snatch a point against Chelsea in a 1-1 draw on Wednesday after Eden Hazard's dazzling opener for the visitors.
Aston Villa were relegated from the Premier League for the first time since it began in 1992 when they suffered their 24th loss of the season in a 1-0 defeat at Old Trafford on Saturday.
The Scottish broadcaster said Murray was self-isolating and still had hopes of competing in the Australian Open next month.
The Premier League kicked off in unique fashion on Saturday as an own goal by Tottenham Hotspur's Kyle Walker gave Manchester United a 1-0 victory in an undistinguished season opener at Old Trafford.
Diego Costa was on target again as Chelsea overcame a defensive West Bromwich Albion 1-0 to return to the top of the Premier League with their ninth victory in a row on Sunday. The Spaniard's second-half strike sent the Blues three points clear of Arsenal, who had taken the overall lead on goals scored on Saturday after seeing off Stoke City 3-1 at the Emirates.
Manchester United were denied by a spirited Stoke City performance as Joe Allen pounced late to secure the visitors their first point at Old Trafford since 1989 in a deserved 1-1 Premier League draw.
IMAGES from the English Premier League matches played on Tuesday
Manchester City suffered their first home Premier League loss in eight months as a shock 3-2 defeat by Crystal Palace on Saturday left Pep Guardiola's champions trailing leaders Liverpool by four points.
A summary of Saturday's matches in the English Premier League.
Liverpool took over at the top of the Premier League table despite being held to a 0-0 draw against Manchester United in a scrappy match on Sunday.
Chelsea's woes continued when the holders were dumped out of the Capital One (League) Cup fourth round following a shootout defeat by Stoke City on Tuesday, while Arsenal suffered a humiliating 3-0 defeat at second tier Sheffield Wednesday.
United down Newcastle after Saints stun Chelsea on a dramatic night in the English Premier League.
Tottenham Hotspur missed the chance to move up to provisional fourth place in the Premier League after relegation-threatened Newcastle United held them to a 2-2 draw with a late equaliser from substitute Joe Willock at St James' Park on Sunday. Images from EPL matches played on Sunday.